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What Is Niagen and How Does It Work?
You may have heard of Niagen in conversations about longevity, energy, or cellular health—but what exactly is it, and how does it work? Niagen is a patented, clinically studied form of nicotinamide riboside (NR), a unique member of the vitamin B3 family. It’s designed to increase levels of NAD+ (nicotinamide adenine dinucleotide)—a molecule essential for powering your cells, supporting metabolism, and promoting healthy aging.
At Medical House Calls, we deliver Niagen as part of our IV Therapy services and Oral Supplement offerings to help clients unlock more energy, sharper focus, and lasting vitality from the inside out. Here’s everything you need to know.
Niagen IV Therapy: The Powerful Precursor to NAD+
What Is Niagen?
Niagen® is the branded name for nicotinamide riboside (NR), a breakthrough vitamin B3 compound that’s been extensively studied for its ability to increase NAD+ levels in the body. NAD+ is a critical coenzyme involved in over 500 cellular processes, including energy production, DNA repair, and inflammation response.
As we age, our NAD+ levels decline dramatically—by as much as 50% by middle age. This loss is linked to fatigue, slower metabolism, brain fog, and signs of premature aging. Niagen helps replenish those NAD+ levels, allowing your cells to function more like they did when you were younger.
How Does Niagen Work?
Once ingested or infused, Niagen is converted into NAD+ inside your cells. NAD+ is the fuel behind your mitochondria—the “batteries” of your cells—and supports everything from cognitive function to skin cell renewal.
Unlike traditional vitamin B3 (niacin), Niagen bypasses the steps that typically lead to uncomfortable side effects like flushing. It’s also more stable and bioavailable than other NAD+ precursors like NMN. In clinical studies, Niagen has been shown to increase NAD+ levels by up to 150% in just weeks.
What Are the Benefits of Niagen?
Lasting Energy, Without the Crash
By replenishing NAD+, Niagen helps revitalize your body’s natural energy systems at the cellular level—without relying on caffeine or sugar. That means sustained energy throughout the day with fewer crashes.
Sharper Focus & Mental Clarity
NAD+ is essential for healthy brain function. Many clients report improved cognitive performance, reduced brain fog, and better mood after consistent use of Niagen therapy.
Healthier Skin from Within
Cellular health shows up in your complexion. Niagen helps promote collagen synthesis, cell repair, and hydration—leaving you with a brighter, more youthful appearance.
Supports DNA Repair & Healthy Aging
Niagen activates enzymes that help repair DNA and defend against oxidative stress, supporting healthy aging and reducing the wear-and-tear associated with daily life.
Boosts Metabolism & Fat Processing
NAD+ also plays a key role in metabolic regulation. Niagen may support better glucose control, fat metabolism, and weight maintenance over time.
How Niagen Compares to Other NAD+ Boosters
| NAD+ Booster | Highlights | Challenges |
| Niagen (NR) | Most clinically studied, well tolerated, highly bioavailable | Premium price point |
| NMN | Up-and-coming, promising data | Less stable, fewer human trials |
| Niacin (B3) | Affordable, traditional | Can cause flushing, GI discomfort |
| NAD+ IV Direct | Fastest absorption | More invasive, can cause side effects during infusion |
According to NiagenPlus.com, Niagen is backed by more than 300 scientific studies, 90+ patents, and partnerships with top researchers worldwide—making it the most trusted NAD+ booster on the market.
How We Deliver Niagen at Medical House Calls
We offer two ways to experience the benefits of Niagen—each designed to fit your goals and lifestyle:
Niagen IV Therapy
- Administered by licensed medical professionals in the comfort of your home
- Higher absorption and faster results
- Ideal for burnout recovery, high performance, or rapid energy restoration
- Available in 500mg and 1,000mg infusions
Niagen Oral Supplement
- Easy daily support
- 1,000mg Tru Niagen® per serving
- Great for maintenance and ongoing NAD+ support
- Clinically proven to raise NAD+ by up to 150%
Is Niagen Safe?
Yes. Niagen is Generally Recognized as Safe (GRAS) by the FDA and has been used safely in numerous human studies. It is free from caffeine, gluten, dairy, and artificial colors. Side effects are rare and typically mild (e.g., slight nausea or flushing at very high doses). Our medical team will guide you on what’s right for your health profile.
Who Should Consider Niagen?
Niagen is ideal for people who want to:
- Feel more energized and focused throughout the day
- Support healthy aging, brain health, or metabolism
- Recover faster from stress, travel, or physical activity
- Improve skin tone and vitality
- Take a science-backed approach to wellness and longevity
Where To Find Niagen?
Niagen is more than just a supplement—it’s a cellular-level solution to energy loss, aging, and poor recovery. Backed by leading science and trusted by thousands, it’s a powerful way to feel better, think clearer, and live younger from the inside out.
To learn more or schedule your personalized Niagen IV Therapy or supplement delivery, text or call Medical House Calls today.
Unlock Vitality with NAD+ Therapy
